Description

Spiro[3.4]Octan-2-One CAS NO 41463-77-8 is a specialized spirocyclic ketone building block of significant interest in advanced organic synthesis. Its unique bridged bicyclic structure makes it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, catalyst development, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional scaffolds.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that leverage its spirocyclic core for enhanced bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated chiral ligands and organocatalysts used in asymmetric synthesis.
• Fragrance and Flavor Chemistry: Employed in the creation of novel synthetic musk compounds and other complex aroma chemicals.
• Material Science Research: Investigated as a monomer or cross-linking agent for developing polymers with unique thermal and mechanical properties.
• Academic and R&D: A valuable tool for methodological studies in organic chemistry, including ring-expansion and rearrangement reactions.

Basic Information

Product Name	Spiro[3.4]Octan-2-One
CAS No.	41463-77-8
Molecular Formula	C8H12O
Molecular Weight	124.18 g/mol
Synonyms	Spiro[3.4]octan-2-one; 2-Spiro[3.4]octanone; Bicyclo[3.3.0]octan-2-one; 1-Oxaspiro[2.3]hexan-4-one (incorrect but sometimes used); Spiro-3,4-octan-2-one
EINECS	Contact for details

Quality Control

Every batch of Spiro[3.4]Octan-2-One is produced and analyzed under strict quality management protocols. We provide comprehensive Certificates of Analysis (COA) that detail purity, identity, and impurity profiles, ensuring traceability and consistency for your critical R&D and scale-up processes. Our quality systems are designed to support cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.