Description

Bis-Cyano-Peg5 is a heterobifunctional polyethylene glycol (PEG) derivative featuring terminal cyano groups. This compound is a critical building block in bioconjugation and materials science, serving as a versatile linker for creating stable, functionalized surfaces and biomolecule-polymer hybrids. It is essential for researchers and manufacturers in the pharmaceutical, diagnostics, and advanced materials sectors who require precise, water-soluble spacers for coupling reactions.

Application

• Bioconjugation Linker: Used to tether proteins, peptides, or antibodies to surfaces, nanoparticles, or other polymers while maintaining bioactivity.
• Polymer Modification: Serves as a functional initiator or terminator in the synthesis of cyano-end-capped PEG polymers for specialized material properties.
• Surface Functionalization: Enables the creation of cyano-terminated self-assembled monolayers (SAMs) on gold, silicon, or other substrates for sensor development.
• Crosslinking Agent: Acts as a hydrophilic crosslinker in hydrogel formulations, leveraging the cyano groups for further chemical modification.
• Pharmaceutical Research: Employed in the development of PEGylated drug conjugates and controlled-release systems.
• Diagnostic Assays: Utilized to functionalize magnetic beads or microplates for immunoassay and biosensor applications.

Basic Information

Product Name	Bis-Cyano-Peg5
CAS No.	41263-79-0
Molecular Formula	C16H28N2O6
Molecular Weight	344.41 g/mol
Synonyms	1-Cyano-11-(2-cyanoethoxy)-3,6,9-trioxaundecane; α,ω-Bis(2-cyanoethoxy)triethylene glycol; PEG5 dinitrile; 3,6,9-Trioxaundecanedinitrile; 2,2'-(Ethane-1,2-diylbis(oxy))bis(acetonitrile) derivative; Bis(2-cyanoethyl) ether of triethylene glycol; NC-PEG5-CN
EINECS	Contact for details

Quality Control

Our Bis-Cyano-Peg5 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent performance for research and production applications. Certificates of Analysis (COA) detailing purity, identity, and moisture content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as specified on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Molecular Weight (NMR)	344.41 ± 5 g/mol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.