Description

3-(2-Bromo-4,5-Dimethoxyphenyl)-2-Cyanoacrylic Acid is a specialized brominated and methoxylated cyanoacrylic acid derivative, serving as a high-value synthetic intermediate. This compound is critical for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for synthesizing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders or possessing specific receptor binding profiles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators that require a brominated, electron-deficient aromatic core.
• Material Science Precursor: Serves as a monomer or cross-linking agent in the development of specialty polymers, dyes, or photoactive materials.
• Organic Synthesis Reagent: Utilized in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) or as a Michael acceptor in nucleophilic addition reactions due to its activated acrylate structure.
• Chemical Biology Probe Development: Acts as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function or cellular processes.

Basic Information

Product Name	3-(2-Bromo-4,5-Dimethoxyphenyl)-2-Cyanoacrylic Acid
CAS No.	41234-19-9
Molecular Formula	C₁₂H₁₀BrNO₄
Molecular Weight	312.12 g/mol
Synonyms	2-Cyano-3-(2-bromo-4,5-dimethoxyphenyl)acrylic acid; (2E)-2-Cyano-3-(2-bromo-4,5-dimethoxyphenyl)prop-2-enoic acid; 3-(2-Bromo-4,5-dimethoxyphenyl)-2-cyano-2-propenoic acid; 2-Bromo-4,5-dimethoxybenzylidenecyanoacetic acid; α-Cyano-3-(2-bromo-4,5-dimethoxyphenyl)acrylic acid; Bromodimethoxyphenyl cyanoacrylic acid
EINECS	Contact for details

Quality Control

Our production of 3-(2-Bromo-4,5-Dimethoxyphenyl)-2-Cyanoacrylic Acid adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.