Description

1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradecane is a high-purity macrocyclic tetraamine ligand, also known as TMC-tacn. This compound is valued for its strong and selective chelating properties towards transition metal ions, forming stable complexes critical for advanced research and industrial catalysis. It is primarily utilized by researchers and manufacturers in the fields of coordination chemistry, catalysis, and materials science for developing novel metal-organic frameworks (MOFs), catalysts, and magnetic resonance imaging (MRI) contrast agents.

Application

• Coordination Chemistry & Catalyst Synthesis: Serves as a key ligand for constructing homogeneous catalysts used in oxidation, polymerization, and organic synthesis reactions.
• MRI Contrast Agent Research: Investigated as a chelating scaffold for gadolinium(III) and other lanthanide ions in the development of next-generation contrast agents.
• Materials Science: Used in the synthesis of metal-organic frameworks (MOFs) and supramolecular assemblies with tailored porosity and functionality.
• Biomimetic Studies: Acts as a model compound for studying metalloenzyme active sites and developing bio-inspired catalysts.
• Analytical Chemistry: Employed in the design of selective ionophores for sensors and separation technologies.
• Radiopharmaceuticals: Explored as a bifunctional chelator for labeling biomolecules with radioisotopes for diagnostic and therapeutic applications.

Basic Information

Item	Detail
Product Name	1,4,8,11-Tetramethyl-1,4,8,11-Tetraazacyclotetradecane
CAS No.	41203-22-9
Molecular Formula	C14H32N4
Molecular Weight	256.44 g/mol
Synonyms	TMC-tacn; 1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradecane; Tetramethylcyclam; 1,4,8,11-Tetramethylcyclam; TMC; 1,4,8,11-Me4[14]aneN4; 1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradeca-4,11-diene (common misnomer for saturated form); N,N',N'',N'''-Tetramethyl-1,4,8,11-tetraazacyclotetradecane
EINECS	Contact for details

Quality Control

Our 1,4,8,11-Tetramethyl-1,4,8,11-tetraazacyclotetradecane is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support compliance with relevant research and quality standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.