Description

L-Norvaline Ethyl Ester Hydrochloride is a protected amino acid derivative, specifically the ethyl ester hydrochloride salt of the non-proteinogenic amino acid L-norvaline. This compound is a crucial chiral building block in organic synthesis, offering a protected carboxyl group and a free amino group for selective peptide coupling and molecular construction. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptides, bioactive compounds, and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Serves as a protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Biochemical Research: Used in enzymatic studies and as a substrate analog to investigate amino acid metabolism and transport mechanisms.
• Agrochemical Development: Employed in the research and synthesis of novel herbicides, pesticides, and plant growth regulators with chiral centers.
• Fine Chemical Synthesis: A versatile intermediate for creating custom-designed molecules in medicinal chemistry and material science.
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	L-Norvaline Ethyl Ester Hydrochloride
CAS No.	40918-51-2
Molecular Formula	C7H16ClNO2
Molecular Weight	181.66 g/mol
Synonyms	L-2-Aminopentanoic Acid Ethyl Ester Hydrochloride; Ethyl L-Norvalinate Hydrochloride; (S)-2-Aminopentanoic Acid Ethyl Ester Hydrochloride; Norvaline Ethyl Ester HCl; H-Nva-OEt·HCl; L-Norvaline Ethyl Ester HCl; L-Norvaline Ethyl Ester Hydrochloride Salt; (S)-Ethyl 2-aminopentanoate hydrochloride
EINECS	Contact for details

Quality Control

Our L-Norvaline Ethyl Ester Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% (L-Isomer)
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.