Description

6-Chloro-2-(4-Chlorophenyl)Quinoline-4-Carbonyl Chloride is a high-purity, multi-functional chemical intermediate with significant synthetic utility. Its reactive carbonyl chloride group and halogenated quinoline core make it a versatile building block for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel quinoline-based drug candidates, including potential antimicrobials, antimalarials, and kinase inhibitors.
• Agrochemical Synthesis: Used to construct advanced fungicides, herbicides, and pesticides, leveraging the bioactivity of the chlorinated quinoline scaffold.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers, dyes, and organic electronic materials.
• Chemical Biology: Employed as a derivatization agent or probe precursor for studying biological targets and pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to clients.

Basic Information

Product Name	6-Chloro-2-(4-Chlorophenyl)Quinoline-4-Carbonyl Chloride
CAS No.	40846-33-1
Molecular Formula	C17H8Cl3NO
Molecular Weight	356.61 g/mol
Synonyms	4-Chlorocarbonyl-6-chloro-2-(4-chlorophenyl)quinoline; 2-(4-Chlorophenyl)-6-chloroquinoline-4-carbonyl chloride; 6-Chloro-2-(p-chlorophenyl)-4-quinolinecarbonyl chloride; Quinoline-4-carbonyl chloride, 6-chloro-2-(4-chlorophenyl)-; 40846-33-1; 2-(4-Chlorophenyl)-6-chloroquinoline-4-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-(4-Chlorophenyl)Quinoline-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis of the acid chloride group. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.