Description

5-Chloro-2-Methylanisole is a versatile halogenated anisole derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in providing a methoxy-protected aromatic ring system with specific substitution patterns for regioselective functionalization. This compound is primarily needed by R&D chemists and process engineers in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted anisole scaffold.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides where the chloromethylanisole structure is integral to biological activity.
• Dye and Pigment Manufacturing: Serves as a precursor in the synthesis of specialized dyes and organic pigments.
• Liquid Crystal Materials: A potential intermediate in the production of liquid crystal compounds for display technologies.
• Organic Synthesis Research: Employed in academic and industrial R&D for cross-coupling reactions, such as Suzuki or Buchwald-Hartwig amination, and other aromatic transformations.
• Fragrance and Flavor Chemistry: Used as a starting material for synthesizing specific aroma chemicals, though typically in advanced, modified forms.

Basic Information

Product Name	5-Chloro-2-Methylanisole
CAS No.	40794-04-5
Molecular Formula	C8H9ClO
Molecular Weight	156.61 g/mol
Synonyms	1-Chloro-4-methoxy-2-methylbenzene; 2-Methyl-5-chloroanisole; 5-Chloro-2-methoxy-1-methylbenzene; 4-Chloro-2-methoxytoluene; 2-Methyl-5-chloromethoxybenzene; 5-Chloro-o-methylanisole; Benzene, 1-chloro-4-methoxy-2-methyl-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-Methylanisole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for synthetic applications. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.