Description

(2R)-3β-Acetoxy-2,3,3Aβ,9Aβ-Tetrahydro-2α-[(Triphenylmethoxy)Methyl]-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-6-One CAS NO 40732-55-6 is a high-purity, complex heterocyclic organic compound featuring a fused furo-oxazolo-pyrimidinone core structure. This molecule is of significant value as a key chiral intermediate in advanced pharmaceutical synthesis, particularly for the development of nucleoside analogs and other active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, high-value therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of novel nucleoside and nucleotide analogs with potential antiviral or anticancer activity.
• Organic Synthesis Research: Used as a specialized reagent in academic and industrial research for constructing complex fused heterocyclic systems.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of target drug candidates.
• Asymmetric Synthesis: Utilized in reactions requiring specific stereochemical control due to its defined (2R) configuration.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API manufacturing.

Basic Information

Product Name	(2R)-3β-Acetoxy-2,3,3Aβ,9Aβ-Tetrahydro-2α-[(Triphenylmethoxy)Methyl]-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-6-One
CAS No.	40732-55-6
Molecular Formula	C31H28N2O6
Molecular Weight	524.57 g/mol
Synonyms	(2R)-3β-Acetoxy-2,3,3aβ,9aβ-tetrahydro-2α-[(triphenylmethoxy)methyl]-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one; 3β-Acetoxy-2α-[(trityloxy)methyl]-2,3,3aβ,9aβ-tetrahydro-6H-furo[2',3':4,5]oxazolo[3,2-a]pyrimidin-6-one (2R)-; 2'-O-Trityl-3'-O-acetyl-5-aza-2'-deoxycytidine derivative; 5-Aza-2'-deoxycytidine intermediate; Furo-oxazolo-pyrimidinone derivative; Trityl-protected nucleoside analog intermediate
EINECS	Contact for details

Quality Control

Our (2R)-3β-Acetoxy-2,3,3Aβ,9Aβ-Tetrahydro-2α-[(Triphenylmethoxy)Methyl]-6H-Furo[2',3':4,5]Oxazolo[3,2-A]Pyrimidin-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, MS). A detailed Certificate of Analysis (COA) confirming identity, purity, and other critical parameters is provided with every shipment to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e.
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.