Description

Dichlorobis(tri-o-tolylphosphine)palladium(II) is a highly specialized organometallic catalyst featuring a sterically hindered tri-o-tolylphosphine ligand. This compound is valued for its exceptional stability and selectivity in cross-coupling reactions, which are fundamental to constructing complex molecular architectures. It is a critical reagent for R&D chemists and process engineers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise catalytic performance.

Application

• Cross-Coupling Catalysis: A premier catalyst for demanding Suzuki-Miyaura, Stille, and Heck cross-coupling reactions, especially with sterically hindered substrates.
• Pharmaceutical Intermediate Synthesis: Enables the efficient construction of carbon-carbon and carbon-heteroatom bonds in the synthesis of active pharmaceutical ingredients (APIs) and complex drug candidates.
• Agrochemical Manufacturing: Used in the production of advanced herbicides, fungicides, and insecticides that require specific aryl-aryl linkages.
• Materials Science Research: Facilitates the synthesis of conjugated polymers, organic semiconductors, and novel ligand systems for electronic and optoelectronic applications.
• Fine Chemical Production: Applied in the manufacture of specialty chemicals, flavors, fragrances, and dyes where high selectivity is paramount.
• Academic & Industrial R&D: A staple reagent in laboratory-scale research for methodological development and scaling up novel synthetic pathways.

Basic Information

Product Name	Dichlorobis(tri-o-tolylphosphine)palladium(II)
CAS No.	40691-33-6
Molecular Formula	C42H42Cl2P2Pd
Molecular Weight	792.03 g/mol
Synonyms	Palladium(II) dichlorobis(tri-o-tolylphosphine); Bis(tri-o-tolylphosphine)palladium(II) dichloride; Dichlorobis[tris(2-methylphenyl)phosphine]palladium; PdCl2[P(o-tolyl)3]2; Tris(2-methylphenyl)phosphine palladium(II) dichloride; o-Tolylphosphine Palladium Catalyst; Pd-P(o-tol)3 complex
EINECS	Contact for details

Quality Control

Every batch of Dichlorobis(tri-o-tolylphosphine)palladium(II) is manufactured and tested under strict quality management systems. We ensure high catalytic activity and lot-to-lot consistency through comprehensive analytical protocols, including NMR, HPLC, and elemental analysis. A Certificate of Analysis (COA) detailing purity, identity, and performance-related specifications is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (argon or nitrogen) for long-term storage and to maintain optimal catalytic activity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (Pd content)	≥ 13.4% (by ICP-OES)
Purity (HPLC)	≥ 98.0%
Solubility	Soluble in common organic solvents (DCM, toluene, THF)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.