Description

3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Butanol is a valuable protected alcohol derivative, serving as a versatile chiral building block and synthetic intermediate in advanced organic synthesis. Its primary value lies in the THP-protected hydroxyl group, which provides stability during multi-step reactions while allowing for selective deprotection under mild acidic conditions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for the development of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in routes requiring protected diol or polyol functionalities.
• Agrochemical Synthesis: Building block for creating complex molecules used in advanced crop protection agents and herbicides.
• Fine Chemical Production: Intermediate in the manufacture of specialty chemicals, including ligands, catalysts, and advanced polymers.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce chirality into target molecules for high-value applications.
• Protecting Group Chemistry: The THP group is used to temporarily mask the alcohol functionality, allowing for selective reactions at other sites on the molecule.
• Research & Development: Critical reagent in academic and industrial R&D labs for exploring new synthetic pathways and novel compound libraries.

Basic Information

Item	Detail
Product Name	3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Butanol
CAS No.	40595-23-1
Molecular Formula	C9H18O3
Molecular Weight	174.24 g/mol
Synonyms	1-Butanol, 3-[(tetrahydro-2H-pyran-2-yl)oxy]-; 3-(Tetrahydro-2H-pyran-2-yloxy)-1-butanol; 3-(THP-Oxy)-1-butanol; 3-O-THP-1-butanol; 1-Butanol, 3-[(tetrahydro-2-pyranyl)oxy]-; 3-(Tetrahydropyran-2-yloxy)butan-1-ol; THP-protected 1,3-butanediol monoether
EINECS	Contact for details

Quality Control

Our 3-[(Tetrahydro-2H-Pyran-2-Yl)Oxy]-1-Butanol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) detailing specifications such as assay, enantiomeric excess (where applicable), and impurity profiles. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is compatible with strong acid/organic solvent conditions but should be kept separate from strong oxidizing agents. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Specific Rotation (if chiral)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.