Description

3,4-Difluorophenylhydrazine Hydrochloride is a high-purity organic building block and reagent essential for advanced chemical synthesis. This compound serves as a critical precursor in the development of active pharmaceutical ingredients (APIs) and complex agrochemicals, where its difluorinated phenylhydrazine structure enables precise molecular modifications. It is primarily sought by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing heterocyclic compounds and other high-value intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and pesticides, leveraging the fluorine atoms for enhanced bioactivity and stability.
• Heterocyclic Chemistry: Essential reagent for constructing pyrazole, indazole, and other nitrogen-containing heterocycles, which are core structures in many bioactive molecules.
• Material Science Research: Employed in the development of specialty polymers and advanced organic electronic materials as a functional monomer or cross-linking agent.
• Chemical Research & Development: Serves as a versatile starting material in academic and industrial R&D labs for method development and exploring new synthetic pathways.

Basic Information

Product Name	3,4-Difluorophenylhydrazine Hydrochloride
CAS No.	40594-37-4
Molecular Formula	C6H5F2N2·HCl
Molecular Weight	194.58 g/mol
Synonyms	(3,4-Difluorophenyl)hydrazine hydrochloride; 1-(3,4-Difluorophenyl)hydrazine hydrochloride; 3,4-DFPH HCl; Hydrazine, (3,4-difluorophenyl)-, hydrochloride; 3,4-Difluoro-phenyl-hydrazine hydrochloride; 3,4-Difluoroaniline hydrazine hydrochloride; 3,4-Difluorophenyl hydrazine HCl
EINECS	Contact for details

Quality Control

Our 3,4-Difluorophenylhydrazine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is subjected to comprehensive analytical testing, including HPLC for assay and purity, and is supplied with a corresponding Certificate of Analysis (COA). We adhere to cGMP principles where applicable, and our quality protocols are designed to meet the stringent requirements of pharmaceutical and advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.