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Tocopheryl Retinoate CAS NO 40516-49-2


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CAS No.:40516-49-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Tocopheryl Retinoate is a sophisticated ester formed by the conjugation of Vitamin E (Tocopherol) and Vitamin A (Retinoic Acid). This unique molecular structure is designed to combine the potent antioxidant and skin-conditioning properties of tocopherol with the renowned cell-communicating and renewing benefits of retinoic acid. It is a highly sought-after active ingredient primarily for the cosmetic and personal care industries, where it is valued for its enhanced stability and skin compatibility compared to pure retinoic acid.

Application

  • Anti-aging and Rejuvenating Skincare Formulations: A key active in serums, creams, and lotions aimed at reducing the appearance of fine lines, wrinkles, and photo-damage.
  • Professional Cosmaceutical Products: Used in high-performance treatments for skin texture improvement, elasticity enhancement, and hyperpigmentation correction.
  • Stabilized Retinoid Delivery Systems: Serves as a pro-retinoid that converts to active retinoic acid in the skin, offering efficacy with potentially reduced irritation.
  • Hair Care Actives: Incorporated into scalp treatments and hair serums to promote a healthy scalp environment and improve hair strength.
  • Pharmaceutical Topical Preparations: Investigated for use in dermatological applications targeting skin disorders and wound healing.
  • Nutricosmetic Supplements: An ingredient in advanced oral supplements designed to support skin health from within.

Basic Information

Item Detail
Product Name Tocopheryl Retinoate
CAS No. 40516-49-2
Molecular Formula C38H56O4
Molecular Weight 576.86 g/mol
Synonyms Retinyl Tocopherol; Vitamin A Vitamin E Ester; Retinoic Acid Tocopheryl Ester; Tocopherol Retinoate; Retinol, ester with α-tocopherol; 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid, ester with (+)-2,5,7,8-tetramethyl-2-(4,8,12-trimethyltridecyl)-6-chromanol
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Quality Control

Our Tocopheryl Retinoate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and purity, to ensure it meets stringent specifications for cosmetic and pharmaceutical-grade ingredients. A Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) in a cool, dry place at 2-8°C for long-term stability. Allow the container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance Yellow to orange viscous liquid or solid
Identification (IR) Conforms to structure
Assay (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 3.0%
Heavy Metals ≤ 10 ppm
Residual Solvents Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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