Description

4-Hydroxy-8-(trifluoromethoxy)quinoline is a high-value, multi-functional heterocyclic building block. This compound matters for its unique molecular architecture, combining a quinoline core with both hydroxy and trifluoromethoxy substituents, which imparts distinct electronic and physicochemical properties. It is primarily needed by researchers and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like antimicrobials, anti-inflammatories, and kinase inhibitors.
• Agrochemical Synthesis: Serves as a crucial precursor in the creation of advanced pesticides and herbicides, leveraging the bioactivity of the quinoline scaffold.
• Material Science Research: Used in the development of organic electronic materials, ligands for catalysis, and fluorescent probes due to its conjugated system.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce the functionalized quinoline moiety into larger molecules.

Basic Information

Product Name	4-Hydroxy-8-(trifluoromethoxy)quinoline
CAS No.	40516-41-4
Molecular Formula	C₁₀H₆F₃NO₂
Molecular Weight	229.16 g/mol
Synonyms	8-(Trifluoromethoxy)-4-quinolinol; 4-Quinolinol, 8-(trifluoromethoxy)-; 4-Hydroxy-8-(trifluoromethoxy)quinoline; 8-Trifluoromethoxyquinolin-4-ol; 40516-41-4; Quinoline, 4-hydroxy-8-(trifluoromethoxy)-
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-8-(trifluoromethoxy)quinoline is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.