Description

4-Chloro-7-Trifluoro Methoxyquinoline is a high-purity, versatile quinoline derivative characterized by its unique halogenated and trifluoromethoxy substitution pattern. This molecular structure makes it a critical advanced intermediate for synthesizing complex active pharmaceutical ingredients (APIs) and specialty agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and advanced material science sectors for developing new compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in antiviral, anticancer, and anti-inflammatory research pipelines.
• Agrochemical Synthesis: Serves as a precursor for developing next-generation herbicides, fungicides, and insecticides, leveraging the stability imparted by the fluorine atoms.
• Material Science Research: Used in the development of organic light-emitting diodes (OLEDs) and other electronic materials due to its quinoline core and electron-withdrawing groups.
• Chemical Biology & Proteomics: Employed as a scaffold or tagging agent in the design of molecular probes and enzyme inhibitors for biochemical studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized heterocycles.

Basic Information

Product Name	4-Chloro-7-Trifluoro Methoxyquinoline
CAS No.	40516-31-2
Molecular Formula	C11H5ClF3NO
Molecular Weight	259.61 g/mol
Synonyms	4-Chloro-7-(trifluoromethoxy)quinoline; 7-(Trifluoromethoxy)-4-chloroquinoline; 4-Chloro-7-trifluoromethoxyquinoline; Quinoline, 4-chloro-7-(trifluoromethoxy)-; 40516-31-2; 4-Chloro-7-trifluoromethoxy-quinoline; 4-Chloro-7-trifluoromethoxy quinoline
EINECS	Contact for details

Quality Control

Every batch of 4-Chloro-7-Trifluoro Methoxyquinoline is manufactured under a strict quality management system. We provide comprehensive analytical documentation to ensure traceability and compliance with your project requirements. Our standard quality commitment includes HPLC purity ≥98% (with higher grades available), identity confirmation via spectroscopic methods, and stringent control of residual solvents and related substances. A detailed Certificate of Analysis (COA) is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.