Description

cis-(2-Amino-Cyclopentyl)-Methanol is a versatile chiral amino alcohol building block of significant importance in advanced organic synthesis. Its value lies in its rigid cyclopentane backbone and bifunctional nature, which provides a defined stereochemical handle for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and chiral catalysts.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, including antiviral agents, neurological therapeutics, and enzyme inhibitors.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis, crucial for producing single-isomer compounds.
• Agrochemical Synthesis: Serves as a building block for creating advanced, stereochemically pure pesticides and herbicides with improved efficacy and environmental profiles.
• Fine Chemical Production: Employed in the manufacture of complex specialty chemicals, flavors, and fragrances where precise stereochemistry is required.
• Peptidomimetics Research: The constrained cyclopentane ring mimics peptide turns, making it valuable in medicinal chemistry for designing stable peptide analogs.
• Polymer Modification: Can be incorporated into polymer chains to introduce functional amino and hydroxyl groups, modifying material properties.

Basic Information

Product Name	cis-(2-Amino-Cyclopentyl)-Methanol
CAS No.	40482-12-0
Molecular Formula	C6H13NO
Molecular Weight	115.17 g/mol
Synonyms	(1R,2S)-2-(Aminomethyl)cyclopentanol; (1S,2R)-2-(Aminomethyl)cyclopentanol; cis-2-(Aminomethyl)cyclopentanol; cis-2-Aminomethylcyclopentanol; (1R,2S)-2-Aminomethyl-1-cyclopentanol; 2-(Aminomethyl)cyclopentanol (cis-); (1S,2R)-rel-2-(Aminomethyl)cyclopentanol
EINECS	Contact for details

Quality Control

Our cis-(2-Amino-Cyclopentyl)-Methanol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and cGMP manufacturing. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformity to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption and potential degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.