Description

2-(3-Butynyloxy)Tetrahydro-2 H-Pyran is a versatile chemical intermediate featuring a protected hydroxyl group and an alkyne functionality. This unique bifunctional structure makes it a valuable building block in organic synthesis, particularly for constructing complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially those requiring alkyne coupling or click chemistry strategies.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and plant growth regulators where the alkyne moiety is incorporated into the final active compound.
• Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers, dendrimers, and functionalized surfaces via its reactive sites.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for metal catalysis and organocatalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized to synthesize molecular probes and tags for bio-conjugation and labeling studies in drug discovery.
• Fine Chemical Production: Acts as a precursor for various fine chemicals and specialty compounds in custom synthesis projects.

Basic Information

Product Name	2-(3-Butynyloxy)Tetrahydro-2 H-Pyran
CAS No.	40365-61-5
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	2-(3-Butyn-1-yloxy)tetrahydro-2H-pyran; 2-(But-3-yn-1-yloxy)tetrahydro-2H-pyran; 3-Butynyl tetrahydropyran-2-yl ether; THP-Protected 3-Butyn-1-ol; Tetrahydropyran-2-yl 3-butynyl ether; 2H-Pyran, tetrahydro-2-(3-butynyloxy)-; 40365-61-5; But-3-yn-1-yl oxan-2-yl ether
EINECS	Contact for details

Quality Control

Our 2-(3-Butynyloxy)Tetrahydro-2 H-Pyran is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.