Description

(As)-6,6'-Dichloro-2,2'-Biphenyldicarboxylic Acid is a high-purity, chiral biphenyl derivative that serves as a critical synthetic intermediate and building block in advanced organic synthesis. Its value lies in its rigid, substituted biphenyl core, which is essential for constructing complex molecules with specific stereochemistry and electronic properties. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral and cardiovascular drug research.
• Agrochemical Synthesis: Used in the development of advanced herbicides and pesticides, where its biphenyl structure contributes to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers due to its conjugated aromatic system.
• Chemical Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Academic & R&D: Fundamental reagent in organic chemistry research for studying structure-activity relationships and novel synthetic pathways.

Basic Information

Product Name	(As)-6,6'-Dichloro-2,2'-Biphenyldicarboxylic Acid
CAS No.	40305-09-7
Molecular Formula	C₁₄H₈Cl₂O₄
Molecular Weight	311.12 g/mol
Synonyms	6,6'-Dichloro[1,1'-biphenyl]-2,2'-dicarboxylic Acid; (As)-6,6'-Dichloro-2,2'-biphenyldicarboxylic acid; 2,2'-Biphenyldicarboxylic acid, 6,6'-dichloro-; 6,6'-Dichlorobiphenyl-2,2'-dicarboxylic Acid; NSC 403051; Biphenyl-2,2'-dicarboxylic acid, 6,6'-dichloro- derivative
EINECS	Contact for details

Quality Control

Our (As)-6,6'-Dichloro-2,2'-Biphenyldicarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with stringent specifications for research and industrial use. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.