Description

5-Bromo-1H-Benzo[D]Imidazole-2-Carboxylic Acid is a high-purity, functionalized benzimidazole derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, brominated scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or acting as protease inhibitors.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators that leverage the benzimidazole core structure.
• Material Science: Serves as a monomer or functional additive in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a scaffold for designing activity-based probes, enzyme inhibitors, and molecular tags for studying biological systems.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting research in heterocyclic and medicinal chemistry.

Basic Information

Product Name	5-Bromo-1H-Benzo[D]Imidazole-2-Carboxylic Acid
CAS No.	40197-20-4
Molecular Formula	C8H5BrN2O2
Molecular Weight	241.04 g/mol
Synonyms	5-Bromo-1H-benzimidazole-2-carboxylic acid; 5-Bromo-2-carboxybenzimidazole; 5-Bromo-2-benzimidazolecarboxylic acid; 2-Carboxy-5-bromobenzimidazole; 40197-20-4; 5-Bromo-1H-1,3-benzodiazole-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-1H-Benzo[D]Imidazole-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.