Description

4-Bromo-5-(1,1-dimethylethyl)-2-thiophenecarboxylic acid is a high-value, substituted thiophene derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both bromine and a bulky tert-butyl group, makes it an essential building block for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the thiophene core contributes to biological activity.
• Material Science: Serves as a monomer or functionalizing agent in the creation of conductive polymers, organic semiconductors, and advanced organic frameworks (MOFs/COFs).
• Ligand and Catalyst Development: The carboxylic acid functionality allows for coordination to metals, making it useful for designing novel catalysts and ligands in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new organic reactions and constructing complex heterocyclic systems.
• Fine Chemical Production: Acts as a specialized intermediate in the custom synthesis of high-value, low-volume chemicals for various industrial applications.

Basic Information

Product Name	4-Bromo-5-(1,1-dimethylethyl)-2-thiophenecarboxylic acid
CAS No.	40196-86-9
Molecular Formula	C9H11BrO2S
Molecular Weight	263.15 g/mol
Synonyms	4-Bromo-5-tert-butyl-2-thiophenecarboxylic acid; 5-tert-Butyl-4-bromothiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 4-bromo-5-(1,1-dimethylethyl)-; 4-Bromo-5-(tert-butyl)thiophene-2-carboxylic acid; 40196-86-9; 4-Bromo-5-tert-butylthiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 4-Bromo-5-(1,1-dimethylethyl)-2-thiophenecarboxylic acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality system is designed to meet the rigorous standards required for pharmaceutical and advanced chemical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.