Description

1,2,5,6-Tetrahydro-6-Methyl-4H-Pyrrolo[3,2,1-Ij]Quinolin-4-One is a high-purity, advanced pharmaceutical intermediate belonging to a class of fused heterocyclic compounds. This compound is valued for its complex molecular architecture, which serves as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing fused ring systems with potential biological activity.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in drug discovery programs.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Utilized in exploratory studies to investigate interactions with biological targets.

Basic Information

Product Name	1,2,5,6-Tetrahydro-6-Methyl-4H-Pyrrolo[3,2,1-Ij]Quinolin-4-One
CAS No.	40135-95-3
Molecular Formula	C₁₃H₁₃NO
Molecular Weight	199.25 g/mol
Synonyms	6-Methyl-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one; 6-Methyl-4-oxo-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinoline; 40135-95-3; Pyrroloquinolinone derivative; Fused tricyclic lactam
EINECS	Contact for details

Quality Control

Our production of 1,2,5,6-Tetrahydro-6-Methyl-4H-Pyrrolo[3,2,1-Ij]Quinolin-4-One adheres to stringent quality management protocols. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all critical specifications are provided and traceable to the production lot. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to preserve stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.