Description

8-Benzyl-2-Oxa-8-Aza-Spiro[4.5]Decan-1-One is a sophisticated spirocyclic heterocyclic compound featuring a benzyl-substituted azaspiro framework. This molecule serves as a versatile and high-value building block in advanced organic synthesis, prized for its unique three-dimensional structure which is crucial for modulating the physicochemical properties of target molecules. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams for developing novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new therapeutic agents, particularly in central nervous system (CNS) and other bioactive molecule libraries.
• Agrochemical Synthesis: Used in the creation of advanced crop protection agents and pesticides, where the spirocyclic core contributes to enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor or core structure for designing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for specialty polymers and advanced materials requiring specific structural motifs.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and protein interactions.

Basic Information

Product Name	8-Benzyl-2-Oxa-8-Aza-Spiro[4.5]Decan-1-One
CAS No.	40117-97-3
Molecular Formula	C15H19NO2
Molecular Weight	245.32 g/mol
Synonyms	8-Benzyl-2-oxa-8-azaspiro[4.5]decan-1-one; 1-Oxa-9-azaspiro[5.5]undecan-2-one, 9-benzyl-; 9-Benzyl-1-oxa-9-azaspiro[5.5]undecan-2-one; 8-Benzyl-8-aza-2-oxaspiro[4.5]decan-1-one; 40117-97-3; Benzyl Azaspiro Decanone Derivative; Spirocyclic Lactam Building Block
EINECS	Contact for details

Quality Control

Our production of 8-Benzyl-2-Oxa-8-Aza-Spiro[4.5]Decan-1-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry for comprehensive characterization and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. Custom synthesis and purity grades (e.g., >97%, >98%, >99%) are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.