Description

Ethyl 7-(2,6-Dimethyl-4-Pyridyl)-1-Ethyl-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate belonging to the quinolone carboxylic acid derivative class. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel antibacterial agents. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the development of next-generation antibiotic therapies and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel quinolone and fluoroquinolone antibiotic candidates.
• Antibacterial Research: Serves as a core scaffold for structure-activity relationship (SAR) studies in medicinal chemistry to develop new antimicrobial agents.
• Fine Chemical Synthesis: Used in custom synthesis and contract manufacturing for producing specialized, high-value chemical entities.
• Biochemical Research: Employed in biochemical assays to study bacterial DNA gyrase and topoisomerase IV inhibition mechanisms.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Ethyl 7-(2,6-Dimethyl-4-Pyridyl)-1-Ethyl-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate
CAS No.	40034-74-0
Molecular Formula	C21H22N2O3
Molecular Weight	350.41 g/mol
Synonyms	Ethyl 1-Ethyl-7-(2,6-dimethyl-4-pyridinyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylate; 1-Ethyl-7-(2,6-dimethylpyridin-4-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid ethyl ester; 7-(2,6-Dimethyl-4-pyridyl)-1-ethyl-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester; ABT-719 Intermediate; Quinolone Carboxylate Ester Derivative; Antibacterial Intermediate; CAS 40034-74-0
EINECS	Contact for details

Quality Control

Our Ethyl 7-(2,6-Dimethyl-4-Pyridyl)-1-Ethyl-1,4-Dihydro-4-Oxoquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.