Description

(R)-(-)-1-Methoxy-2-Propanol is a chiral, high-purity solvent and versatile chiral building block. Its value lies in its specific optical rotation, which makes it essential for applications requiring enantiomeric purity and controlled stereochemistry. This compound is particularly needed by the pharmaceutical, agrochemical, and fine chemical industries for asymmetric synthesis, chiral resolution, and as a specialty solvent for sensitive reactions.

Application

• As a chiral auxiliary or resolving agent in asymmetric synthesis for pharmaceutical intermediates.
• As a specialty solvent for chiral catalysts and reagents in enantioselective reactions.
• In the research and development of active pharmaceutical ingredients (APIs) requiring specific stereochemistry.
• As a precursor for the synthesis of other chiral compounds in fine chemical manufacturing.
• In the formulation of high-performance coatings and inks where its specific properties are advantageous.
• For analytical applications as a reference standard or mobile phase component in chiral chromatography.

Basic Information

Product Name	(R)-(-)-1-Methoxy-2-Propanol
CAS No.	4984-22-9
Molecular Formula	C4H10O2
Molecular Weight	90.12 g/mol
Synonyms	(R)-1-Methoxy-2-propanol; (R)-(-)-Propylene glycol monomethyl ether; (R)-PGME; (R)-1-Methoxypropan-2-ol; (R)-Methyl propyl ether glycol; (R)-Methoxyisopropanol; (R)-2-Methoxy-1-methylethanol; (R)-(-)-Methylglycol ether
EINECS	225-642-4

Quality Control

Our (R)-(-)-1-Methoxy-2-Propanol is manufactured under strict quality systems to ensure high enantiomeric purity and chemical consistency. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, optical rotation, and impurity profile. We adhere to cGMP principles where applicable, ensuring reliability for critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and maintain purity. Recommended storage temperature is between 15°C and 25°C.

Specification

Item	Specification
Appearance	Colorless clear liquid
Identification (IR)	Conforms
Assay (GC)	≥ 98.0%
Optical Rotation [α]20/D	-15.0° to -17.0° (c=1, H2O)
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Specific Gravity (20/20°C)	0.920 - 0.930
Refractive Index (n20/D)	1.400 - 1.405

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.