Description

(22S,23S,25R)-23-Bromo-5α-Spirostane is a high-purity, steroidal brominated spirostane derivative. This compound serves as a critical synthetic intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors for the synthesis of novel steroid-based therapeutics and as a key building block in complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel steroid-based active pharmaceutical ingredients (APIs) and potential drug candidates.
• Reference Standard: Used as a certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.
• Biochemical Research: Employed in academic and industrial research to study steroid biosynthesis pathways, enzyme inhibition, and receptor binding activities.
• Process Chemistry: Serves as a starting material or intermediate in the development and scale-up of synthetic routes for complex organic molecules.
• Fine Chemical Synthesis: Utilized in the preparation of specialized steroidal compounds for various high-value applications.

Basic Information

Product Name	(22S,23S,25R)-23-Bromo-5α-Spirostane
CAS No.	4947-69-7
Molecular Formula	C27H43BrO3
Molecular Weight	495.54 g/mol
Synonyms	23-Bromo-5α-spirostan; 23-Bromospirostan; (22S,23S,25R)-23-Bromospirostan; 23-Bromo-5α-spirostane; 5α-Spirostan-23β-ol, 23-bromo-; 23-Bromo-5α-spirostan-3β-ol (related structure); Bromospirostane; 4947-69-7 (CAS Index Name)
EINECS	Contact for details

Quality Control

Our (22S,23S,25R)-23-Bromo-5α-Spirostane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.