Description

n-Octyl L-2-Pyrrolidone-5-Carboxylate is a high-purity, specialty chemical ester derived from L-pyroglutamic acid. This compound serves as a versatile, lipophilic intermediate and functional additive, prized for its ability to modify solubility and enhance skin penetration in advanced formulations. It is primarily sought after by R&D and production teams in the pharmaceutical, cosmetic, and agrochemical industries for synthesizing active ingredients and developing sophisticated delivery systems.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs and active pharmaceutical ingredients (APIs) to improve lipid solubility and bioavailability.
• Cosmetic & Personal Care Formulations: Acts as a skin penetration enhancer and emollient in anti-aging serums, moisturizers, and topical treatments.
• Agrochemical Synthesis: Serves as a key building block for creating lipophilic derivatives of bioactive compounds, such as herbicides and fungicides.
• Chemical Research & Development: Employed as a chiral synthon and protecting group reagent in organic synthesis and process chemistry.
• Specialty Polymer Additive: Functions as a plasticizer or compatibilizer in specific polymer systems requiring tailored solubility parameters.

Basic Information

Product Name	n-Octyl L-2-Pyrrolidone-5-Carboxylate
CAS No.	4931-70-8
Molecular Formula	C₁₃H₂₃NO₃
Molecular Weight	241.33 g/mol
Synonyms	L-Pyroglutamic Acid Octyl Ester; Octyl (S)-(-)-2-Pyrrolidone-5-carboxylate; (S)-5-Oxo-2-pyrrolidinecarboxylic Acid Octyl Ester; L-Pyroglutamic Acid n-Octyl Ester; (-)-PCA Octyl Ester; 5-Oxo-L-proline Octyl Ester; 4931-70-8; L-Pyroglutamate Octyl Ester
EINECS	225-568-9

Quality Control

Our n-Octyl L-2-Pyrrolidone-5-Carboxylate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including chiral purity verification and impurity profiling, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) documenting identity, purity, and specific tests are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed when not in use to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation [α]²⁰D	-20° to -24° (c=1 in CHCl₃)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.