Description

n-(N(Alpha)-(tert-Butyloxycarbonyl)Alanyl)-N,N'-Dicyclohexylurea is a specialized Boc-protected amino acid derivative used as a critical building block in organic synthesis. This compound matters for its role in facilitating the controlled synthesis of peptides and complex organic molecules, where protecting group chemistry is essential. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic peptides, peptidomimetics, and other bioactive compounds.

Application

• Peptide Synthesis Intermediate: A key reagent in solid-phase and solution-phase peptide synthesis (SPPS) for the controlled incorporation of alanine or other modified residues.
• Pharmaceutical Research & Development: Used in the discovery and development of peptide-based drugs, hormone analogs, and enzyme inhibitors.
• Protecting Group Chemistry: Serves as a source of the Boc-Ala moiety, enabling selective protection and deprotection strategies in multi-step organic syntheses.
• Bioconjugation: Employed in the synthesis of labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Academic Research: Utilized in university and institutional labs for studying peptide structure-activity relationships (SAR) and developing new synthetic methodologies.
• Combinatorial Chemistry: A valuable building block for creating diverse chemical libraries for high-throughput screening in drug discovery.

Basic Information

Product Name	n-(N(Alpha)-(tert-Butyloxycarbonyl)Alanyl)-N,N'-Dicyclohexylurea
CAS No.	4909-43-7
Molecular Formula	C21H37N3O4
Molecular Weight	395.54 g/mol
Synonyms	Boc-Ala-N,N'-Dicyclohexylurea; N-(N-Boc-L-alanyl)-N,N'-dicyclohexylurea; (tert-Butoxycarbonyl)alanyl dicyclohexylurea; Boc-Ala-DCU; N-(tert-Butoxycarbonyl)alanyl-N,N'-dicyclohexylurea; N-(Nα-(tert-Butoxycarbonyl)alanyl)-N,N'-dicyclohexylurea; N-(Boc-L-alanyl)-N,N'-dicyclohexylurea; 1-(N-Boc-alanyl)-3,3-dicyclohexylurea
EINECS	Contact for details

Quality Control

Our n-(N(Alpha)-(tert-Butyloxycarbonyl)Alanyl)-N,N'-Dicyclohexylurea is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong acids and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.