Description

(2S)-1,2,3,4-Tetrahydro-8-Hydroxy-4-Oxoquinoline-2-Carboxylic Acid is a high-purity chiral intermediate and building block of significant interest in advanced organic synthesis. Its value lies in its unique quinoline carboxylic acid structure, which serves as a versatile scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), particularly in the areas of quinolone-based therapeutics and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: A key chiral building block in the research and development of novel quinolone and naphthyridone-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Research: Serves as a versatile scaffold for constructing complex heterocyclic compounds in medicinal chemistry and process development.
• Biochemical Research: Used as a precursor or reference standard in studies targeting enzymes or biological pathways where the quinoline core is relevant.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value organic compounds requiring a defined stereochemistry.

Basic Information

Product Name	(2S)-1,2,3,4-Tetrahydro-8-Hydroxy-4-Oxoquinoline-2-Carboxylic Acid
CAS No.	4886-42-4
Molecular Formula	C₁₀H₉NO₄
Molecular Weight	207.18 g/mol
Synonyms	(2S)-1,2,3,4-Tetrahydro-8-hydroxy-4-oxo-2-quinolinecarboxylic acid; (S)-1,2,3,4-Tetrahydro-8-hydroxy-4-oxoquinoline-2-carboxylic acid; L-8-Hydroxy-1,2,3,4-tetrahydro-4-oxoquinoline-2-carboxylic acid; (S)-8-Hydroxy-1,2,3,4-tetrahydro-4-oxo-2-quinolinecarboxylic acid; 8-Hydroxy-1,2,3,4-tetrahydro-4-oxoquinoline-2(S)-carboxylic acid; (2S)-THQ-2-COOH; A potential metabolite precursor of quinolone antibiotics.
EINECS	Contact for details

Quality Control

Our (2S)-1,2,3,4-Tetrahydro-8-Hydroxy-4-Oxoquinoline-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.