Description

Apovincamine is a naturally occurring alkaloid derivative, recognized for its specific pharmacological activity and structural significance. This compound serves as a critical intermediate and reference standard in the research and development of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and manufacturers of fine chemicals and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex vinca alkaloid derivatives and related nootropic or cerebroactive agents.
• Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in analytical laboratories.
• Biochemical Research: Employed in neuroscience and pharmacology studies to investigate mechanisms related to cerebral blood flow and cognitive function.
• Fine Chemical Synthesis: Serves as a starting material or precursor for the preparation of specialized compounds in medicinal chemistry.
• Active Pharmaceutical Ingredient (API) Development: Investigated for its potential direct use or as a metabolite in the development of new drug formulations.

Basic Information

Product Name	Apovincamine
CAS No.	4880-92-6
Molecular Formula	C21H24N2O2
Molecular Weight	336.43 g/mol
Synonyms	Apovincamine; (+)-Apovincamine; Vincamone; Eburnamonine; (3α,16α)-Eburnamenine-14-carboxylic acid methyl ester; L-625; NSC 209661; Apovincaminic acid methyl ester
EINECS	Contact for details

Quality Control

Our Apovincamine is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide full traceability and a Certificate of Analysis (COA) with each shipment, detailing parameters such as assay, related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.