Description

Benzene, 1-[(Difluoromethyl)Sulfonyl]-4-Methyl- is a specialized organosulfur compound featuring a difluoromethylsulfonyl group, a key structural motif valued for its unique electronic and steric properties. This compound is primarily utilized as a high-value intermediate in advanced organic synthesis, particularly in the development of pharmaceuticals and agrochemicals. Research and development teams in fine chemical, pharmaceutical, and material science industries require this building block for creating novel molecules with enhanced biological activity or specific material characteristics.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring sulfonamide or difluoromethyl motifs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the difluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a monomer or precursor in the development of specialty polymers, liquid crystals, and advanced materials with specific electronic properties.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the difluoromethylsulfonyl group into target molecules, enabling structure-activity relationship (SAR) studies.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	Benzene, 1-[(Difluoromethyl)Sulfonyl]-4-Methyl-
CAS No.	4837-17-6
Molecular Formula	C8H8F2O2S
Molecular Weight	206.21 g/mol
Synonyms	4-Methyl-α,α-difluorobenzenemethanesulfonic Acid; 1-Methyl-4-((difluoromethyl)sulfonyl)benzene; p-Tolyl Difluoromethyl Sulfone; α,α-Difluoro-p-tolylsulfonylmethane; 4-Methylbenzenesulfonyl Difluoromethane; (Difluoromethyl)(4-methylphenyl)sulfone; p-(Difluoromethylsulfonyl)toluene
EINECS	Contact for details

Quality Control

Our production of Benzene, 1-[(Difluoromethyl)Sulfonyl]-4-Methyl- adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and incompatible materials. Due to its fluoride/strong alkali reactivity profile, ensure proper segregation in storage areas.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (GC)	≥ 96.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.