Description

(S)-2-Amino-3-Ethoxy-Propionic Acid Hydrochloride is a high-purity, non-proteinogenic amino acid derivative, specifically the hydrochloride salt of the (S)-enantiomer. This compound is a critical chiral building block in the synthesis of complex pharmaceutical intermediates and active pharmaceutical ingredients (APIs). It is essential for research and production in the pharmaceutical, biotechnology, and fine chemical sectors, where precise stereochemistry and high purity are paramount for efficacy and regulatory compliance.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including enzyme inhibitors and receptor modulators.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to incorporate a unique ethoxy-substituted alanine residue into peptide chains.
• Proteomics & Biochemical Research: Serves as a specialized reagent for studying enzyme mechanisms, protein structure, and metabolic pathways.
• Asymmetric Synthesis Catalyst: Can be utilized as a precursor for chiral ligands or organocatalysts in asymmetric carbon-carbon bond-forming reactions.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	(S)-2-Amino-3-Ethoxy-Propionic Acid Hydrochloride
CAS No.	4775-82-0
Molecular Formula	C5H12ClNO3
Molecular Weight	169.61 g/mol
Synonyms	(S)-2-Amino-3-ethoxypropanoic acid hydrochloride; (S)-3-Ethoxyalanine hydrochloride; L-3-Ethoxyalanine hydrochloride; (2S)-2-Amino-3-ethoxypropanoic acid hydrochloride; H-L-3-Ethoxy-Ala-OH·HCl; (S)-α-Amino-β-ethoxypropionic acid hydrochloride; 2-Amino-3-ethoxypropionic acid hydrochloride (S-isomer)
EINECS	Contact for details

Quality Control

Our (S)-2-Amino-3-Ethoxy-Propionic Acid Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets stringent specifications for pharmaceutical R&D and cGMP applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and compliance with customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider using a desiccator or inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.