Description

n-Acetyl-D-Mannosamine is a key monosaccharide derivative and an essential biochemical precursor in the biosynthesis of sialic acids. This high-purity intermediate is critical for research and production in advanced glycobiology and pharmaceutical development. It is primarily utilized by biotechnology, pharmaceutical, and life science research industries for applications ranging from metabolic pathway studies to the synthesis of complex glycoconjugates and novel therapeutics.

Application

• Sialic Acid Biosynthesis: Essential precursor for the enzymatic and chemoenzymatic synthesis of N-acetylneuraminic acid (Neu5Ac) and other sialic acid derivatives.
• Glycoconjugate & Vaccine Development: Used in the production of sialylated oligosaccharides, glycoproteins, and glycolipids for vaccine candidates and biotherapeutic agents.
• Metabolic Research & Cell Biology: A vital tool for studying sialic acid metabolism, cell surface engineering, and glycan-mediated cell signaling pathways.
• Enzyme Substrate & Inhibitor Studies: Serves as a substrate for sialyltransferases and other glycosyltransferases in enzymatic assays and inhibitor screening.
• Nutritional & Cosmetic Applications: Investigated for use in specialized nutraceuticals and high-end cosmetic formulations targeting skin hydration and barrier function.
• Chemical Synthesis Intermediate: Building block for the synthesis of more complex carbohydrates, glycomimetics, and labeled compounds for analytical standards.

Basic Information

Product Name	n-Acetyl-D-Mannosamine
CAS No.	4773-29-9
Molecular Formula	C8H15NO6
Molecular Weight	221.21 g/mol
Synonyms	ManNAc; D-Mannosamine, N-acetyl-; N-Acetylmannosamine; 2-Acetamido-2-deoxy-D-mannose; N-Acetyl-D-mannosamine; Acetylmannosamine; 2-Acetamido-2-deoxymannose; N-Acetyl-2-amino-2-deoxy-D-mannopyranose
EINECS	225-322-8

Quality Control

Our n-Acetyl-D-Mannosamine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent screening, to ensure it meets the stringent requirements of research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	+30.0° to +35.0° (c=1 in H2O)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.