Description

1,4-Dioxaspiro[4.5]Decan-6-Carboxylic Acid is a versatile spirocyclic building block and protected form of a cyclohexanone derivative. This compound is highly valued in organic synthesis for its ability to introduce functionalized cyclohexyl motifs while protecting sensitive ketone groups. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of complex active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of various drug candidates, particularly those targeting the central nervous system.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a precursor for flavors, fragrances, and other specialty organic compounds.
• Academic & Industrial R&D: Employed in methodological studies and as a model substrate for developing new synthetic transformations.
• Material Science: Potential building block for polymers and advanced organic materials with specific structural properties.

Basic Information

Product Name	1,4-Dioxaspiro[4.5]Decan-6-Carboxylic Acid
CAS No.	4746-93-4
Molecular Formula	C9H14O4
Molecular Weight	186.21 g/mol
Synonyms	6-Carboxy-1,4-dioxaspiro[4.5]decane; Cyclohexanone, 4-(carboxymethyl)-, ethylene ketal; 1,4-Dioxaspiro[4.5]decane-6-carboxylic acid; 2-Oxaspiro[4.5]decane-3-carboxylic acid, 8-oxa- (related); Ketal-protected 4-(carboxymethyl)cyclohexanone; Ethylene ketal of 4-(carboxymethyl)cyclohexanone
EINECS	Contact for details

Quality Control

Our 1,4-Dioxaspiro[4.5]Decan-6-Carboxylic Acid is manufactured under strict quality management systems. Each batch is subjected to rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical specifications. Our quality commitment ensures the material meets the high standards required for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect purity and stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.