Description

2-Hydroxy-2,2-Bis(2-Thienyl) Acetic Acid is a specialized organic compound featuring a central acetic acid moiety substituted with two thiophene rings, making it a valuable synthon for heterocyclic chemistry. This compound matters for its role as a key chiral intermediate in the synthesis of complex molecules, particularly in the pharmaceutical sector. It is primarily needed by research and development chemists and process engineers in the fine chemical, agrochemical, and advanced material industries for constructing novel thiophene-based structures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block for the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiophene heterocycles.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the thienyl group imparts specific biological activity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis, enhancing the efficiency of stereoselective reactions.
• Material Science Research: Employed in the development of organic semiconductors, conductive polymers, and other advanced electronic materials due to the electron-rich thiophene units.
• Fine Chemical Production: Utilized as a specialized intermediate for custom synthesis and the manufacture of high-value, low-volume chemicals.

Basic Information

Product Name	2-Hydroxy-2,2-Bis(2-Thienyl) Acetic Acid
CAS No.	4746-63-8
Molecular Formula	C10H8O3S2
Molecular Weight	240.30 g/mol
Synonyms	α-Hydroxy-α,α-di(2-thienyl)acetic acid; 2,2-Di(thiophen-2-yl)-2-hydroxyacetic acid; Di(2-thienyl)glycolic acid; 2-Thiopheneglycolic acid, 2,2-di-2-thienyl-; (Hydroxydi-2-thienyl)acetic acid; 2,2-Bis(2-thienyl)-2-hydroxyacetic acid; 2,2-Di-2-thienyl-2-hydroxyethanoic acid
EINECS	Contact for details

Quality Control

Our 2-Hydroxy-2,2-Bis(2-Thienyl) Acetic Acid is produced under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, related substances, and residual solvents. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.