Description

5-Chloroisatoic Anhydride is a versatile and high-value heterocyclic building block used in advanced organic synthesis. This compound is critical for the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals due to its reactive anhydride and halogenated aromatic structure. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of quinazolinone and quinoline-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced activity.
• Dye and Pigment Manufacturing: Used in the production of specialized heterocyclic dyes and optical brighteners.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of advanced polymers and functional materials.
• Chemical Biology Probes: Utilized to create tagged molecules and probes for studying biological pathways and enzyme activity.

Basic Information

Product Name	5-Chloroisatoic Anhydride
CAS No.	4743-17-3
Molecular Formula	C8H4ClNO3
Molecular Weight	197.57 g/mol
Synonyms	5-Chloro-1H-3,1-benzoxazine-2,4-dione; 5-Chloro-2H-3,1-benzoxazine-2,4(1H)-dione; 5-Chloro-2,4-dihydro-1H-3,1-benzoxazine-2,4-dione; 5-Chloroisatoic acid anhydride; 5-Chloroanthranilic acid cyclic anhydride; Isatoic Anhydride, 5-chloro-; 5-Chloro-1H-benzo[d][1,3]oxazine-2,4-dione
EINECS	225-254-8

Quality Control

Our 5-Chloroisatoic Anhydride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical and fine chemical applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	208°C - 212°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.