Description

2-Amino-1-(4-Nitrophenyl)Ethan-1-One Hydrochloride Hydrate is a key organic intermediate characterized by its amino-ketone hydrochloride salt structure. This compound is valued for its role as a versatile building block in the synthesis of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily sought by research institutions and industrial manufacturers involved in developing active pharmaceutical ingredients (APIs), fine chemicals, and specialty dyes.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of various heterocyclic compounds and potential drug candidates, particularly those targeting neurological or infectious diseases.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its nitro and amino functional groups.
• Fine Chemical Production: Serves as a building block for creating complex organic molecules used in material science and specialty chemistry.
• Dye and Pigment Intermediate: Utilized in the synthesis of azo dyes and other colored compounds due to the presence of the nitrophenyl group.
• Biochemical Research: Employed in laboratory settings for studying enzyme inhibition or as a standard in analytical method development.
• Academic & R&D: A valuable reagent for organic chemistry research and teaching in university and corporate laboratories.

Basic Information

Product Name	2-Amino-1-(4-Nitrophenyl)Ethan-1-One Hydrochloride Hydrate
CAS No.	4740-22-1
Molecular Formula	C8H9N2O3 • HCl • xH2O
Molecular Weight	216.63 (Anhydrous HCl salt)
Synonyms	2-Amino-1-(4-nitrophenyl)ethanone hydrochloride hydrate; 4'-Nitro-2-aminoacetophenone hydrochloride; 1-(4-Nitrophenyl)-2-aminoethanone hydrochloride; p-Nitro-α-aminoacetophenone hydrochloride; 2-Amino-4'-nitroacetophenone hydrochloride; 4-Nitro-2-aminoacetophenone HCl; α-Amino-p-nitroacetophenone hydrochloride
EINECS	Contact for details

Quality Control

Our 2-Amino-1-(4-Nitrophenyl)Ethan-1-One Hydrochloride Hydrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay, impurity profile, and residual solvents, supporting compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.