Description

Octahydro-4,7-Methano-1H-Indene-1,2-Diol is a specialized bicyclic diol compound with a unique, rigid molecular framework. This structure makes it a valuable chiral building block and intermediate in advanced organic synthesis, particularly for creating complex molecules with defined stereochemistry. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and fine chemical industries for applications requiring high-purity, stereochemically defined intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its bicyclic structure contributes to biological activity.
• Fine Chemical Building Block: Employed in asymmetric synthesis and catalysis research to construct complex natural products and specialty chemicals.
• Ligand and Catalyst Development: Its diol functionality allows it to be used in the preparation of chiral ligands for metal-catalyzed reactions.
• Polymer Chemistry: Acts as a monomer or cross-linking agent for producing specialty polymers with enhanced thermal and mechanical properties.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing specific aroma chemicals with camphor-like or woody notes.

Basic Information

Item	Detail
Product Name	Octahydro-4,7-Methano-1H-Indene-1,2-Diol
CAS No.	4728-34-1
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	1,2-Dihydroxyoctahydro-4,7-methano-1H-indene; Bicyclo[2.2.1]heptane-2,3-diol, 1,7,7-trimethyl- (8CI); 2,3-Norbornanediol, 1,7,7-trimethyl-; 1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol; Fenchone glycol; Dihydroxyfenchane; (1R,2S,3R,4S)-1,7,7-Trimethylbicyclo[2.2.1]heptane-2,3-diol (for specific isomer)
EINECS	225-214-6

Quality Control

Our Octahydro-4,7-Methano-1H-Indene-1,2-Diol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support compliance with ICH Q7 guidelines and can tailor specifications to meet specific pharmacopeial (USP/EP) or customer-defined requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after initial opening to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (for specified isomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.