Description

m-Dioxane-4-Methanol is a versatile heterocyclic building block and specialty solvent with significant utility in advanced organic synthesis. Its unique structure, featuring both a dioxane ring and a hydroxymethyl group, makes it a valuable intermediate for creating complex molecules in pharmaceutical and agrochemical research. This compound is particularly sought after by R&D chemists and process development scientists working on novel active ingredients, polymer modifiers, and high-performance materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel drug candidates, particularly those requiring chiral or polyether-like scaffolds.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators.
• Polymer Chemistry: Acts as a monomer or chain transfer agent for modifying polymer properties such as solubility, flexibility, and biodegradability.
• Crosslinking Agent: Utilized in the formulation of specialty resins, coatings, and adhesives where its hydroxyl functionality enables network formation.
• Solvent for Specialty Reactions: Functions as a polar aprotic solvent for reactions sensitive to more common solvents, offering unique solvation properties.
• Ligand and Catalyst Preparation: Employed as a precursor for synthesizing chelating ligands used in homogeneous catalysis and metal complexation.

Basic Information

Product Name	m-Dioxane-4-Methanol
CAS No.	4728-06-7
Molecular Formula	C5H10O3
Molecular Weight	118.13 g/mol
Synonyms	1,3-Dioxan-5-ylmethanol; 5-(Hydroxymethyl)-1,3-dioxane; 1,3-Dioxane-5-methanol; 5-Hydroxymethyl-1,3-dioxane; meta-Dioxane-4-methanol; NSC 403796
EINECS	225-212-5

Quality Control

Our m-Dioxane-4-Methanol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including identity confirmation by FT-IR and NMR, and purity determination by GC or HPLC. A detailed Certificate of Analysis (COA) is supplied with each shipment, documenting all relevant specifications. Our quality commitment ensures the material is suitable for demanding applications in research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Due to its nature as an easily oxidized compound, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after the container has been opened. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.440 - 1.445
Density (20°C)	1.18 - 1.22 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.