Description

Benzonitrile, 2,3,6-Trichloro- CAS NO 4681-11-2 is a halogenated aromatic nitrile derivative, serving as a versatile and high-value synthetic intermediate in advanced chemical manufacturing. Its unique substitution pattern makes it a critical building block for constructing complex molecules in pharmaceutical and agrochemical research. This compound is essential for chemists and process engineers in the fine chemical, pharmaceutical, and crop protection industries seeking to develop new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for compounds requiring a substituted benzonitrile core.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trichloro-substituted ring provides specific biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of monomers or additives for high-performance polymers and liquid crystals.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Dye and Pigment Intermediate: Can be utilized in the production of specialized colorants and functional dyes.

Basic Information

Product Name	Benzonitrile, 2,3,6-Trichloro-
CAS No.	4681-11-2
Molecular Formula	C7H2Cl3N
Molecular Weight	206.46 g/mol
Synonyms	2,3,6-Trichlorobenzonitrile; 2,3,6-Trichlorobenzenecarbonitrile; Benzonitrile, trichloro-; NSC 403107; Trichlorobenzonitrile (mixed isomers may be implied); BOT (abbreviation in some contexts); 2,3,6-Trichloro-benzonitril
EINECS	Contact for details

Quality Control

Our 2,3,6-Trichlorobenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including GC, HPLC, and NMR to confirm identity and quantify impurities. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.