Description

4'-Chloro-Biphenyl-3-Carboxylic Acid is a high-purity, versatile organic intermediate with a defined halogenated biphenyl structure. This compound is valued for its role as a key building block in the synthesis of more complex molecules, particularly in advanced pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical, pharmaceutical, and material science industries for constructing active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and fungicides, leveraging its biphenyl core for biological activity.
• Liquid Crystal & OLED Materials: Serves as a building block for creating specialized organic compounds used in display technologies and organic light-emitting diodes (OLEDs).
• Polymer Modification: Employed to introduce functional carboxylic acid groups into polymer chains, altering material properties like adhesion and solubility.
• Chemical Research & Development: A standard reagent in academic and industrial labs for studying cross-coupling reactions and synthesizing complex polycyclic aromatic systems.
• Dye & Pigment Intermediate: Utilized in the production of specialized colorants and pigments requiring a halogenated biphenyl backbone.

Basic Information

Product Name	4'-Chloro-Biphenyl-3-Carboxylic Acid
CAS No.	4655-10-1
Molecular Formula	C13H9ClO2
Molecular Weight	232.66 g/mol
Synonyms	3-(4-Chlorophenyl)benzoic acid; 4'-Chloro-3-biphenylcarboxylic Acid; [1,1'-Biphenyl]-3-carboxylic acid, 4'-chloro-; 4-Chlorobiphenyl-3-carboxylic Acid; 3-Carboxy-4'-chlorobiphenyl; NSC 403107; Biphenyl-3-carboxylic acid, 4'-chloro derivative
EINECS	Contact for details

Quality Control

Our 4'-Chloro-Biphenyl-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures the material meets the stringent requirements for research and cGMP-grade manufacturing applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	205 - 210 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.