Description

(E)-3-Chloroprop-2-En-1-Ol is a versatile chlorinated allylic alcohol building block with significant synthetic utility. Its reactive vinyl chloride and hydroxyl functional groups make it a valuable intermediate for constructing more complex molecules through cross-coupling, substitution, and addition reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules containing allylic or propenyl motifs.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides, where its structure can be incorporated into bioactive compounds.
• Polymer & Material Science: Acts as a monomer or cross-linking agent for the development of specialty polymers, resins, and functional materials.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Heck, Suzuki) and nucleophilic substitution reactions to introduce chloropropenyl groups.
• Ligand & Catalyst Preparation: Useful for synthesizing novel chiral or functionalized ligands for asymmetric catalysis and metal complexes.
• Flavor & Fragrance Industry: Can be utilized as a precursor for certain aroma chemicals and synthetic flavors.

Basic Information

Item	Details
Product Name	(E)-3-Chloroprop-2-En-1-Ol
CAS No.	4643-05-4
Molecular Formula	C3H5ClO
Molecular Weight	92.52 g/mol
Synonyms	(E)-3-Chloro-2-propen-1-ol; trans-3-Chloroallyl Alcohol; 3-Chloro-2-propen-1-ol (E)-; 2-Propen-1-ol, 3-chloro-, (2E)-; (E)-3-Chloroallyl Alcohol; 3-Chloro-trans-2-propen-1-ol; NSC 9375; (E)-3-Chloroprop-2-enol
EINECS	Contact for details

Quality Control

Our (E)-3-Chloroprop-2-En-1-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (HPLC, GC) and spectroscopic methods (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. Due to its light-sensitive nature, containers should be kept in the original outer packaging or a dark storage cabinet.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Isomeric Purity ((E)-isomer)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.