Description

o-Prop-2-Ynyl-Hydroxylamine is a versatile organic building block featuring both a hydroxylamine and a terminal alkyne functional group. This bifunctional nature makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily sought after by R&D chemists and process development scientists in the life sciences and specialty chemical sectors for constructing novel molecular scaffolds and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially those requiring hydroxylamine or oxime linkages.
• Click Chemistry Reagent: The terminal alkyne group enables efficient Huisgen 1,3-dipolar cycloaddition (click reactions) with azides for bioconjugation and polymer chemistry.
• Ligand Synthesis: Used in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Serves as a functional monomer or cross-linking agent for creating polymers with tailored properties.
• Agrochemical Research: Intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators.
• Material Science: Building block for advanced organic materials and surface functionalization.

Basic Information

Product Name	o-Prop-2-Ynyl-Hydroxylamine
CAS No.	4616-54-0
Molecular Formula	C₃H₅NO
Molecular Weight	71.08 g/mol
Synonyms	Propargylhydroxylamine; 2-Propyn-1-amine, N-hydroxy-; N-Hydroxyprop-2-yn-1-amine; 2-Propynylhydroxylamine; 1-Hydroxyamino-2-propyne; Propargyloxyamine; N-(Prop-2-yn-1-yl)hydroxylamine; 3-Hydroxyaminopropyne
EINECS	Contact for details

Quality Control

Our o-Prop-2-Ynyl-Hydroxylamine is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing key parameters such as assay, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our customers in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized and should be handled with care to minimize exposure to air.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.