Description

4-Bromoisothiazole-3-Carboxylic Acid is a versatile brominated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in its functionalized isothiazole ring, which serves as a key precursor for constructing complex molecules in pharmaceutical and agrochemical research. This compound is primarily needed by R&D chemists and process development scientists working in medicinal chemistry, crop protection, and advanced material science.

Application

• Pharmaceutical Intermediates: A crucial synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-infective drug discovery programs.
• Agrochemical Synthesis: Used as a building block for creating new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its electron-deficient heterocyclic core.
• Chemical Biology Probes: Utilized to create tagged or modified molecular probes for studying biological pathways and protein interactions.
• Custom Synthesis and Contract Manufacturing: A key starting material for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-Bromoisothiazole-3-Carboxylic Acid
CAS No.	4576-88-9
Molecular Formula	C4H2BrNO2S
Molecular Weight	207.03 g/mol
Synonyms	3-Carboxy-4-bromoisothiazole; 4-Bromo-1,2-thiazole-3-carboxylic acid; 4-Bromoisothiazole-3-carboxylic acid; 4-Bromo-3-isothiazolecarboxylic acid; Isothiazole-3-carboxylic acid, 4-bromo-; 4-Bromo-1,2-thiazole-3-carboxylic acid; 4-Bromoisothiazole-3-carboxylic acid (principal name)
EINECS	Contact for details

Quality Control

Our 4-Bromoisothiazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with full batch traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.