Description

Sodium Sulfamethoxazole is the sodium salt form of the widely used sulfonamide antibiotic, sulfamethoxazole. This water-soluble derivative is critical for formulating stable, injectable, and oral liquid pharmaceutical preparations where precise dosing and bioavailability are paramount. It is an essential active pharmaceutical ingredient (API) and intermediate for manufacturers in the human and veterinary pharmaceutical sectors, particularly for producing combination therapies.

Application

• Pharmaceutical API: Primary use as the active ingredient in antibacterial formulations, often in combination with trimethoprim (co-trimoxazole).
• Injectable Solutions: Formulation of sterile injectable products for systemic infections requiring rapid therapeutic action.
• Oral Suspensions & Syrups: Production of pediatric and geriatric-friendly liquid dosage forms for improved patient compliance.
• Veterinary Medicine: Manufacture of antibacterial treatments for livestock, poultry, and companion animals.
• Intermediate for Further Synthesis: Used in chemical synthesis to produce other sulfonamide derivatives or prodrugs.
• Research & Development: Serves as a standard or reagent in microbiological and pharmacological research studies.

Basic Information

Product Name	Sodium Sulfamethoxazole
CAS No.	4563-84-2
Molecular Formula	C10H10N4NaO3S
Molecular Weight	281.27 g/mol
Synonyms	Sulfamethoxazole Sodium; Sulfamethoxazole Sodium Salt; Sodium N1-(5-Methyl-3-isoxazolyl)sulfanilamide; 4-Amino-N-(5-methyl-3-isoxazolyl)benzenesulfonamide Sodium Salt; SMZ-Na; Sulfamethoxazolum Natricum; SMX-Na; Co-trimoxazole component (sodium salt form)
EINECS	Contact for details

Quality Control

Our Sodium Sulfamethoxazole is manufactured under strict quality management systems. It is typically tested to meet in-house specifications aligned with major pharmacopoeial standards for related substances. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles to ensure compliance with your formulation requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (5% Solution)	9.0 - 11.0
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.