Description

2,2',5,5'-Tetramethoxybiphenyl is a high-purity biphenyl derivative characterized by its four methoxy substituents, which impart unique electronic and steric properties. This compound serves as a versatile and critical advanced intermediate in the synthesis of complex organic molecules, particularly in the development of specialty chemicals and functional materials. It is primarily utilized by pharmaceutical research organizations, agrochemical developers, and manufacturers of liquid crystal and OLED materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for compounds requiring a rigid, substituted biphenyl core.
• Liquid Crystal (LC) Material Synthesis: Used as a precursor for creating mesogenic units in liquid crystal displays (LCDs) due to its stable, planar biphenyl structure with tunable side chains.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a core structure in the development of host or transport materials for OLED devices, leveraging its electron-donating methoxy groups.
• Agrochemical Intermediate: Employed in the research and production of advanced pesticides and herbicides where the tetramethoxybiphenyl scaffold provides specific biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing sophisticated chiral or polydentate ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer and Resin Modifier: Incorporated into polymer chains to enhance thermal stability, optical properties, or to introduce cross-linking sites in high-performance resins.

Basic Information

Product Name	2,2',5,5'-Tetramethoxybiphenyl
CAS No.	4555-64-0
Molecular Formula	C16H18O4
Molecular Weight	274.31 g/mol
Synonyms	2,2',5,5'-Tetramethoxy-1,1'-biphenyl; 1,1'-Biphenyl, 2,2',5,5'-tetramethoxy-; Biphenyl-2,2',5,5'-tetramethyl ether; 2,2',5,5'-Tetramethoxydiphenyl; NSC 403796; Tetramethoxybiphenyl
EINECS	Contact for details

Quality Control

Our 2,2',5,5'-Tetramethoxybiphenyl is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat sources and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.