Description

4-Chloroquinoline-2-Carbonitrile is a versatile and high-value heterocyclic building block, recognized for its role as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a chloroquinoline core and a reactive nitrile group, makes it indispensable for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of quinoline-based drug candidates, including potential antimalarial, anticancer, and antiviral agents.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline scaffold imparts biological activity.
• Organic Light-Emitting Diodes (OLEDs): Serves as a building block for electron-transport or emissive layer materials in electronic displays and lighting.
• Coordination Chemistry & Ligand Design: The nitrile and chlorine functional groups allow it to act as a ligand or be modified to create complexing agents for metal catalysis.
• Dye and Pigment Manufacturing: Employed in the synthesis of specialized quinoline-derived colorants and fluorescent markers.
• Academic & Contract Research: A valuable reagent for methodological studies in organic synthesis, including cross-coupling and cyclization reactions.

Basic Information

Product Name	4-Chloroquinoline-2-Carbonitrile
CAS No.	4552-43-6
Molecular Formula	C10H5ClN2
Molecular Weight	188.61 g/mol
Synonyms	2-Cyano-4-chloroquinoline; 4-Chloro-2-cyanoquinoline; 4-Chloroquinoline-2-carbonitrile; Quinoline, 4-chloro-2-cyano-; 2-Quinolinecarbonitrile, 4-chloro-
EINECS	Contact for details

Quality Control

Our 4-Chloroquinoline-2-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.