Description

Benzene, (1-Methyl-2-Propyn-1-Yl)- is a specialized aromatic compound featuring a propargyl substituent, making it a valuable synthon in advanced organic synthesis. This compound matters for its role as a key building block in the production of complex molecules, offering a unique combination of aromatic stability and alkyne reactivity. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing novel chemical entities and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates.
• Agrochemical Synthesis: Used in the development and production of advanced pesticides, herbicides, and plant growth regulators.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and advanced organic materials.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex molecular architectures via Sonogashira and other cross-coupling reactions.
• Ligand and Catalyst Development: Utilized in the preparation of specialized ligands for metal catalysis and organocatalysts.
• Fine Chemical Production: Integral to the manufacture of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	Benzene, (1-Methyl-2-Propyn-1-Yl)-
CAS No.	4544-28-9
Molecular Formula	C10H10
Molecular Weight	130.19 g/mol
Synonyms	1-Methyl-2-propyn-1-ylbenzene; (1-Methyl-2-propynyl)benzene; α-Methylpropargylbenzene; 2-Propyn-1-yl, 1-methyl-, benzene deriv.; Propargylbenzene, α-methyl-; Benzene, (1-methyl-2-propynyl)-; 1-Phenyl-2-butyn-1-ol (related precursor); α-Methylbenzylacetylene
EINECS	Contact for details

Quality Control

Our Benzene, (1-Methyl-2-Propyn-1-Yl)- is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available for every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and oxidizing agents. The container should be kept tightly sealed to prevent moisture ingress and potential evaporation.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Total impurities ≤ 3.0%
Specific Gravity (20°C)	0.92 - 0.96
Refractive Index (20°C)	1.520 - 1.530

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.