Description

n-[4-(Aminosulphonyl)Phenyl]-3-Oxobutyramide is a specialized organic compound featuring both a sulfonamide and a β-ketoamide functional group. This unique molecular structure makes it a valuable intermediate in the synthesis of more complex molecules, particularly in the pharmaceutical sector. It is primarily sought after by research and development chemists and manufacturers in the fine chemical and active pharmaceutical ingredient (API) industries.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting enzymes where the sulfonamide moiety is pharmacologically active.
• Chemical Research & Development: Serves as a versatile precursor for creating libraries of compounds in medicinal chemistry programs for screening and lead optimization.
• Agrochemical Synthesis: Used in the development of advanced herbicides or fungicides, leveraging its reactive amide and ketone groups.
• Dye and Pigment Manufacturing: Acts as an intermediate in the production of specialized azo dyes or pigments, where the aromatic amine derivative can be diazotized.
• Material Science Research: Investigated for use in the synthesis of monomers or additives for polymers with specific thermal or mechanical properties.

Basic Information

Product Name	n-[4-(Aminosulphonyl)Phenyl]-3-Oxobutyramide
CAS No.	4542-32-9
Molecular Formula	C10H12N2O4S
Molecular Weight	256.28 g/mol
Synonyms	4-Amino-N-(3-oxobutanoyl)benzenesulfonamide; 3-Oxo-N-[4-(sulfamoyl)phenyl]butyramide; 4'-(Aminosulfonyl)acetoacetamilide; N-(4-Sulfamoylphenyl)-3-oxobutyramide; Acetoacet-4-sulfanilamide; AS-101; NSC 403169
EINECS	Contact for details

Quality Control

Our n-[4-(Aminosulphonyl)Phenyl]-3-Oxobutyramide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.