Description

5-Bromo-2-Iodo-Biphenyl is a high-purity halogenated biphenyl derivative, a crucial building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which enables selective cross-coupling reactions for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura and other palladium-catalyzed cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides, leveraging its halogen sites for molecular diversification.
• Material Science Research: Serves as a monomer or building block for creating organic electronic materials, such as OLEDs and conductive polymers.
• Ligand Preparation: Utilized in the synthesis of specialized ligands for catalysis and coordination chemistry.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Academic & R&D: A versatile reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	5-Bromo-2-Iodo-Biphenyl
CAS No.	4510-78-5
Molecular Formula	C12H8BrI
Molecular Weight	359.00 g/mol
Synonyms	2-Iodo-5-bromobiphenyl; [1,1'-Biphenyl]-2-iodo-5-bromo; 5-Bromo-2-iodobiphenyl; 2-Bromo-5-iodobiphenyl (registry number check required); Biphenyl, 5-bromo-2-iodo-; 5-Bromo-2-iodo-1,1'-biphenyl
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Iodo-Biphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored away from direct light exposure to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.