Description

1-Oxaspiro[5.5]undecan-2-one is a versatile spirocyclic lactone compound that serves as a valuable synthetic intermediate and building block in advanced organic chemistry. Its unique bridged bicyclic structure makes it a key precursor for the synthesis of complex molecules, including pharmaceuticals, agrochemicals, and specialty fragrances. This high-purity compound is essential for research and development chemists, process scale-up teams, and manufacturers in the fine chemical and life sciences industries seeking reliable, high-quality intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs) and novel drug candidates, particularly those requiring spirocyclic or complex bridged ring systems.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and plant growth regulators where its specific ring structure imparts desired biological activity.
• Fragrance and Flavor Chemistry: Serves as a precursor for musk-like odorants and complex aroma chemicals due to its macrocyclic lactone-related structure.
• Material Science Research: Employed in the development of novel polymers, resins, and specialty materials that benefit from its rigid, spirocyclic core.
• Organic Synthesis & Methodology Development: A valuable substrate for chemists developing new catalytic reactions, ring-forming transformations, and asymmetric synthesis protocols.
• Chemical Reference Standard: Used as an analytical standard in quality control laboratories for method development and verification in related chemical processes.

Basic Information

Product Name	1-Oxaspiro[5.5]undecan-2-one
CAS No.	4481-78-1
Molecular Formula	C10H16O2
Molecular Weight	168.23 g/mol
Synonyms	1-Oxaspiro[5.5]undecan-2-one; 2-Oxaspiro[5.5]undecan-3-one; Spiro[5.5]undecane-1,6-dione, 2-oxa-; 2-Oxa-1,6-dioxaspiro[5.5]undecane (related); δ-Lactone, spirocyclic; Spirocyclic ε-caprolactone analog
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[5.5]undecan-2-one is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods (IR, NMR) and purity assessment by chromatography (GC/HPLC) to ensure it meets exacting standards for research and industrial use. A Certificate of Analysis (COA) detailing specific results for purity, appearance, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.