Description

2-Amino-3-Methylbutyronitrile is a versatile organic nitrile compound with a branched-chain amino group, serving as a critical chiral building block in advanced synthesis. Its value lies in its bifunctional reactivity, enabling its use as a precursor for non-proteinogenic amino acids and complex heterocyclic structures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, particularly for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, including protease inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its nitrile functionality.
• Fine Chemical Production: Serves as a building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Peptidomimetic Research: Integral in medicinal chemistry for creating peptide analogs and conformationally restricted scaffolds.
• Chemical Biology Probes: Utilized in the development of labeled compounds and probes for studying enzymatic mechanisms.

Basic Information

Product Name	2-Amino-3-Methylbutyronitrile
CAS No.	4475-96-1
Molecular Formula	C5H10N2
Molecular Weight	98.15 g/mol
Synonyms	2-Amino-3-methylbutanenitrile; 3-Methyl-2-aminobutyronitrile; L-Isoleucine nitrile; (2S)-2-Amino-3-methylbutanenitrile; 2-Amino-3-methylbutyric acid nitrile; α-Amino-β-methylbutyronitrile; 2-Azanyl-3-methylbutanenitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-3-Methylbutyronitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The product is light-sensitive and should be handled accordingly.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.